Protein Details: Gap junction beta-4 protein

Protein ID

ICDB_Pro_1586

Protein Name

Gap junction beta-4 protein

Gene Name

GJB4

Organism

Homo sapiens (Human)

Length

266 amino acids

AlphaFoldDB

AF-Q9NTQ9-F1-model_v4.pdb

Function

Sequence

MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCPNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNLSKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCYISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEIFGPRHRRPRCRECLPDTCPPYVLSQGGHPEDGNSVLMKAGSAPVDAGGYP

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Erythrokeratodermia Variabilis Et Progressiva 2 and Erythrokeratodermia Variabilis Et Progressiva 1

Location

DOI ID

10.1038/ng1285; 10.1038/nature04727; 10.1101/gr.2596504; 10.1016/s0002-9297(07)62957-7; 10.1002/humu.9023; 10.1046/j.1523-1747.2003.12080.x; 10.1002/ajmg.a.32744

RefSeq

NP_694944.1; XP_011538981.1